New Packard Study Provides New Understanding of TDP-43 in ALS

Packard scientist Phil Wong and colleagues have published a new study in Science that outlines the normal function of the ALS-linked protein TDP-43 and spells out more clearly how loss of this function contributes to disease. Unlike other RNA-binding proteins, TDP-43...

Ice bucket challenge helped spur ALS discovery, scientists say

Money raised from the Ice Bucket Challenge that went viral last year has significantly boosted research into ALS, scientists at Johns Hopkins say.   They say it has helped them to understand more about a dysfunctional protein - TDP-43 - a mystery scientists have...